An internal card, a direct cable connection will always be more reliable, faster and consistent, than a USB or remote connection. What they won't be is as convenient as a device external to the computer. Of course, if you have a laptop, and internal card may not be available.
There are the speed limitations of USB II connections, plus the additional overhead of additional software that is used, whereas an internal card probably has its own RAM and will be less reliant on software and software drivers to get it to work.
USB connections also have a speed limit, while internal connections will not have speed limitations, but are limited by the hardware that is created. BUT ....you can't beat the convenience and the ability to swap external devices from one unit to another.
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