No no no, don't go buying anything at radioshack or bestbuy. If you do, it's gonna be a 50/50 chance that they'll work. I bought the usb to serial at radioshack and bestbuy neither worked with my vista. I finally bought one that worked with vista. It's called "Keyspan". If you go to their website it's, gonna be just as exenssive as radioshack and bestbuy, but try other online sources to buy them coughcoughamazoncoughcough.