use a larger fuse? No, for real, sounds like a dead short on the rem wire. Use a DMM and check for shorts on or around the amps rem, and power connections. If its shorting when you turn the HU on, then it could be the rem. Disconect it, jump the rem from the power and see if it still shorts.
wow think you would have relized somethings wrong befor you blew all 6 fuses!
anyway. check you power wire for any shorts or any damage to it. make sure you have tight connections everywhere. and youll pobly want to get a bigger fuse assuming your running 4guage id get like a 150a fuse.
what brand of woofers and coil impedance and if they r series or parallel... check the woofers with a multi meter also... i'll check back on this one... i have to know the woofers because current can make a coil act like a fuse, thus a faulty coil can be a problem as well...